Bacteriophage-based Solution for the Treatment of Implant Related Infections

Inventor(s): Professor Iain McNamara
Member Trust: Norfolk and Norwich University Hospitals NHS Foundation Trust (in collaboration with University of East Anglia, Quadram Institute (formerly the Institute of Food Research) and ANGLIAN AGRI-TECH VENTURES

Award Amount: £84,420

Award Duration: 9 months

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Background: Bacterial infection accounts for 25% of revision hip and knee replacement operations resulting in surgical site infections (SSIs) in orthopaedic surgery. Revision of infected implants is associated with substantial morbidity and economic cost. The cost of revising infected knee replacements alone has been estimated at £160million in the UK. This project will develop a new biologic-based product coating (bacteriophage) for implanted prosthetic materials to eradicate bacterial infections in revision hip and knee joint replacement surgery.

Project Plan for Award: The award brings together four parties and will cover both the initial production and testing of the bacteriophage in an in-house model system with a view to designing a path for commercialisation.

The support from the MedTech Accelerator will allow us to set up a collaboration between industry, hospital and medical partners that would have been otherwise difficult to fund.”


Professor Iain McNamara
Norfolk and Norwich University Hospitals NHS Foundation Trust